I try to avoid all those iffy chemicals found lurking in nutrition labels. A chemical that does not occur in food naturally and has been 'invented'/developed in the laboratory is not something I am inclined to want to ingest. HFCS comes high in that category. Here's the latest study that suggests that HFCS isn't good for health: cnn report on corn syrup.
And here's a YouTube lecture about the harm that High-Fructose Corn Syrup does to the body: The Bitter Truth. You'll need to settle down to watch for well over an hour, but it's entertainingly delivered and very interesting, and if it persuades you to avoid HFCS then it will be time well spent.