Women who donate their eggs for fertility research are at risk from life-threatening side effects, University of Padua scientists warn in a new study.

Fertility research drugs put egg donors at risk

Extract:

"Women who donate their eggs for research are at risk from life-threatening side effects, scientists warn in a new study.

They say that the powerful drugs given to the volunteers to help increase the number of eggs they produce can cause paralysis, limb amputation and even death.

The warning comes days before the results of a review into a controversial decision to allow doctors to harvest eggs from healthy volunteers for research purposes.

The Human Fertilisation and Embryology Authority (HFEA) is expected to endorse its policy, which provoked an outcry when it was announced last year. But the safety of egg donation is questioned by Italian experts.

In their study, 34 women suffered severe reactions to the hormone-stimulating drugs used. The researchers, at the University of Padua, found that most of those affected had previously enjoyed good health. An analysis of doctors' reports since the early 1990s revealed that 60 per cent of the accidents involved blood clots in the head and neck.

The study, in the journal Thrombosis and Thrombolysis, concludes that the number of side effects would rise as the number of assisted reproduction techniques increased and that doctors using the drugs need a better understanding of the potential risks."


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