article in the Telegraph
"Leptin, an appetite-suppressing hormone, was greeted with great excitement more than a decade ago with many academics believing that it could be a cure for obesity.
But hopes soon dimmed when it was found that overweight people became unresponsive to Leptin very quickly due to the development of resistance in the brain.
Now its reputation could be revived after researchers have found a way to stop the brain blocking its influence.
Scientists at Harvard University have found that the substances Buphenyl (4-PBA) and Tauroursodeoxycholic acid (TUDCA), both available in pills, stop the brain from ignoring Leptin.
Their findings, published in Cell Metabolism, suggest that it once again could help the growing weight problem around the world.
"Everyone in the field thought they would get the Nobel," said Dr Umut Ozcan, who led the study, about the period when Leptin was first discovered."
Overweight people do NOT need appetite suppressants to lose weight. - They need to reduce their problem of fluid retention/salt sensitivity to lose weight. They need to be told the truth. - Eating less food/fewer calories actually encourages weight gain, not weight loss. - Here is information about how overweight people can lose excess weight safely, quickly and very easily indeed, without taking dodgy pharmaceutical junk:
Lose weight safely, reduce your risk of most cancers, high blood pressure, type 2 diabetes, stroke, heart disease, heart attack, vascular dementia, osteopenia, osteoporosis, hypercholesterolaemia, depression, liver and kidney problems, and improve your health in many other ways without drugs, hunger or expense by eating less salt! - Try it! - You will feel so much better!and FAT RETENTION
I can be contacted via my website if you need my further help. My help is free.